Structure of PDB 2nl9 Chain A

Receptor sequence
>2nl9A (length=142) Species: 9606,10090 [Search protein sequence]
DDLYRQSLEIISRYLREQATGSGAAGRRALETLRRVGDGVQRNHETAFQG
MLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKT
INQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE
3D structure
PDB2nl9 Structural insights into the degradation of Mcl-1 induced by BH3 domains.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V220 H224 M231 K234 L235 S245 R248 V249 H252 V253 D256 N260 G262 R263 V265 T266 F318 F319 V40 H44 M51 K54 L55 S65 R68 V69 H72 V73 D76 N80 G82 R83 V85 T86 F138 F139
BS02 ZN A D313 E317 D133 E137
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2nl9, PDBe:2nl9, PDBj:2nl9
PDBsum2nl9
PubMed17389404
UniProtP97287|MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Gene Name=Mcl1);
Q07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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