Structure of PDB 2naa Chain A

Receptor sequence
>2naaA (length=94) Species: 10090 (Mus musculus) [Search protein sequence]
GAMEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWH
QCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHD
3D structure
PDB2naa Structural basis for PHDVC5HCHNSD1-C2HRNizp1 interaction: implications for Sotos syndrome.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.357: [histone H3]-lysine(36) N-dimethyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C9 C12 H31 C34 C9 C12 H31 C34
BS02 ZN A C21 C26 C47 H50 C21 C26 C47 H50
BS03 ZN A C52 C55 C71 H74 C52 C55 C71 H74
BS04 ZN A C63 C66 C90 H93 C63 C66 C90 H93
External links
PDB RCSB:2naa, PDBe:2naa, PDBj:2naa
PDBsum2naa
PubMed26896805
UniProtO88491|NSD1_MOUSE Histone-lysine N-methyltransferase, H3 lysine-36 specific (Gene Name=Nsd1)

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