Structure of PDB 2n14 Chain A

Receptor sequence
>2n14A (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
QINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQH
MVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLAT
3D structure
PDB2n14 Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 49H A M53 L56 G57 I60 M61 Q71 H72 V92 M31 L34 G35 I38 M39 Q49 H50 V70 PDBbind-CN: -logKd/Ki=5.33,Kd=4.7uM
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:2n14, PDBe:2n14, PDBj:2n14
PDBsum2n14
PubMed26812210
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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