Structure of PDB 2mzd Chain A

Receptor sequence
>2mzdA (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
ATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKGCK
RKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQK
3D structure
PDB2mzd Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R9 R10 S12 I13 Q14 R15 I17 S19 S35 K38 M39 V42 I59 Q62 A65 L66 Y69 H70 H73 C74 R9 R10 S12 I13 Q14 R15 I17 S19 S35 K38 M39 V42 I59 Q62 A65 L66 Y69 H70 H73 C74
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2mzd, PDBe:2mzd, PDBj:2mzd
PDBsum2mzd
PubMed25753752
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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