Structure of PDB 2ms1 Chain A

Receptor sequence
>2ms1A (length=55) Species: 11786 (Murine leukemia virus) [Search protein sequence]
ATVVSGQKQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPR
PQTSL
3D structure
PDB2ms1 A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R17 R18 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42 R17 R18 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42 PDBbind-CN: Kd=4nM
BS02 ZN A C26 H34 C39 C26 H34 C39
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ms1, PDBe:2ms1, PDBj:2ms1
PDBsum2ms1
PubMed25209668
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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