Structure of PDB 2ms0 Chain A

Receptor sequence
>2ms0A (length=55) Species: 11786 (Murine leukemia virus) [Search protein sequence]
ATVVSGQKQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPR
PQTSL
3D structure
PDB2ms0 A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A Q7 K8 Q9 R11 Q12 G13 G14 E15 R17 R18 S19 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42 Q7 K8 Q9 R11 Q12 G13 G14 E15 R17 R18 S19 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42
BS02 ZN A C26 H34 C39 C26 H34 C39
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ms0, PDBe:2ms0, PDBj:2ms0
PDBsum2ms0
PubMed25209668
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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