Structure of PDB 2mqv Chain A

Receptor sequence
>2mqvA (length=56) Species: 11786 (Murine leukemia virus) [Search protein sequence]
ATVVSGQKQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPR
PQTSLL
3D structure
PDB2mqv A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K8 Q9 Q12 R16 R17 R18 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42 K8 Q9 Q12 R16 R17 R18 D22 R23 Q25 A27 Y28 K30 W35 A36 K41 K42 PDBbind-CN: Kd=33nM
BS02 ZN A C26 C29 H34 C39 C26 C29 H34 C39
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2mqv, PDBe:2mqv, PDBj:2mqv
PDBsum2mqv
PubMed25209668
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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