Structure of PDB 2mnz Chain A

Receptor sequence
>2mnzA (length=55) Species: 9606 (Homo sapiens) [Search protein sequence]
AVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK
CLAQE
3D structure
PDB2mnz The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V307 D308 S317 G318 N319 E321 L324 L325 L326 D328 P347 G349 W351 V2 D3 S12 G13 N14 E16 L19 L20 L21 D23 P42 G44 W46
BS02 ZN A C312 C315 H335 C338 C7 C10 H30 C33
BS03 ZN A C330 D331 C353 C356 C25 D26 C48 C51
External links
PDB RCSB:2mnz, PDBe:2mnz, PDBj:2mnz
PDBsum2mnz
PubMed24952722
UniProtQ9UGL1|KDM5B_HUMAN Lysine-specific demethylase 5B (Gene Name=KDM5B)

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