Structure of PDB 2mki Chain A

Receptor sequence
>2mkiA (length=203) Species: 9606 (Homo sapiens) [Search protein sequence]
SHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESK
SYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIR
PWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY
AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKP
YVL
3D structure
PDB2mki A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins
ChainA
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K66 F68 G71 P96 H97 Y110 F112 Y136 I144 K147 P148 Q150 R152 F176 R182 K215 G216 K251 V254 K14 F16 G19 P44 H45 Y58 F60 Y84 I92 K95 P96 Q98 R100 F124 R130 K163 G164 K199 V202 PDBbind-CN: Kd=15.8uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0045182 translation regulator activity
Biological Process
GO:0006417 regulation of translation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2mki, PDBe:2mki, PDBj:2mki
PDBsum2mki
PubMed24990967
UniProtQ17RY0|CPEB4_HUMAN Cytoplasmic polyadenylation element-binding protein 4 (Gene Name=CPEB4)

[Back to BioLiP]