Structure of PDB 2mjp Chain A

Receptor sequence
>2mjpA (length=184) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
KIYFATGNPNKIKEANIILKDLKDVEIEQIKISYPEIQGTLEEVAEFGAK
WVYNILKKPVIVEDSGFFVEALNGFPGTYSKFVQETIGNEGILKLLEGKD
NRNAYFKTVIGYCDENGVRLFKGIVKGRVSEEIRSKGYGFAYDSIFIPEE
EERTFAEMTTEEKSQISHRKKAFEEFKKFLLDRI
3D structure
PDB2mjp Structure-based identification of a novel NTPase from Methanococcus jannaschii.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.66: XTP/dITP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A N17 N19 K20 E23 S74 G75 S89 K90 F115 F149 H177 R178 N8 N10 K11 E14 S65 G66 S80 K81 F106 F140 H168 R169
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0035870 dITP diphosphatase activity
GO:0036220 ITP diphosphatase activity
GO:0036222 XTP diphosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0009117 nucleotide metabolic process
GO:0009143 nucleoside triphosphate catabolic process
GO:0009146 purine nucleoside triphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2mjp, PDBe:2mjp, PDBj:2mjp
PDBsum2mjp
PubMed10404228
UniProtQ57679|IXTPA_METJA dITP/XTP pyrophosphatase (Gene Name=MJ0226)

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