Structure of PDB 2mjh Chain A

Receptor sequence

>2mjhA (length=142) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]

LPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKI
MVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAA
LEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPA

3D structure

PDB

2mjh Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1.

Chain

Resolution

N/A

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	N220 V222 G223 L226 G227 P228 R229 G230 A233 K234 K243 I244 M245 V246 R247 A260 R262 N266 W267 E307 G308 D310 K313 R314 L317 M318 L320 A321 Y327 R328 P329 M330	N26 V28 G29 L32 G33 P34 R35 G36 A39 K40 K49 I50 M51 V52 R53 A66 R68 N72 W73 E113 G114 D116 K119 R120 L123 M124 L126 A127 Y133 R134 P135 M136	PDBbind-CN: Kd=0.061uM

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

External links

PDB	RCSB:2mjh, PDBe:2mjh, PDBj:2mjh
PDBsum	2mjh
PubMed	24838563
UniProt	Q17339\|GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (Gene Name=gld-1)