Structure of PDB 2mf8 Chain A

Receptor sequence

>2mf8A (length=75) Species: 10090 (Mus musculus)

LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPT
PGCDGSGHITGNYASHRSLSGCPRA

3D structure

• PDB: 2mf8 A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers.
• Chain: A
• Resolution: N/A

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	H812 I813 T814 Y817 S819 R821 S824 G825 A842 S866 L867	H14 I15 T16 Y19 S21 R23 S26 G27 A44 S68 L69
BS02	dna	A	L800 S822 L823 H856 T858 Y861 S863 R865 S868 G869	L2 S24 L25 H58 T60 Y63 S65 R67 S70 G71
BS03	ZN	A	C802 C807 H820 C826	C4 C9 H22 C28
BS04	ZN	A	C846 T848 C851 C870	C48 T50 C53 C72

Gene Ontology

Molecular Function

• GO:0008270 zinc ion binding

Biological Process

• GO:0006355 regulation of DNA-templated transcription

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:2mf8, PDBe:2mf8, PDBj:2mf8
• PDBsum: 2mf8
• PubMed: 24097990
• UniProt: Q8CFC2|MYT1_MOUSE Myelin transcription factor 1 (Gene Name=Myt1)