Structure of PDB 2mc1 Chain A

Receptor sequence
>2mc1A (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
GHMQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIK
YNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTT
LQFPFKE
3D structure
PDB2mc1 Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E677 R678 A679 R696 Q697 R698 E704 A706 K716 H717 K719 E731 K732 K755 S756 E17 R18 A19 R36 Q37 R38 E44 A46 K56 H57 K59 E71 K72 K95 S96
External links
PDB RCSB:2mc1, PDBe:2mc1, PDBj:2mc1
PDBsum2mc1
PubMed23955592
UniProtP15498|VAV_HUMAN Proto-oncogene vav (Gene Name=VAV1)

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