Structure of PDB 2mak Chain A

Receptor sequence
>2makA (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMASSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH
EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR
3D structure
PDB2mak STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E336 S337 S339 S340 Y342 P344 L351 H355 E31 S32 S34 S35 Y37 P39 L46 H50
BS02 peptide A G-5 K366 Q372 L373 A376 K377 G379 I383 K386 G1 K61 Q67 L68 A71 K72 G74 I78 K81
Gene Ontology
Molecular Function
GO:0005246 calcium channel regulator activity

View graph for
Molecular Function
External links
PDB RCSB:2mak, PDBe:2mak, PDBj:2mak
PDBsum2mak
PubMed24351972
UniProtQ13586|STIM1_HUMAN Stromal interaction molecule 1 (Gene Name=STIM1)

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