Structure of PDB 2m5e Chain A

Receptor sequence
>2m5eA (length=73) Species: 5888 (Paramecium tetraurelia) [Search protein sequence]
MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMI
READIDGDGHINYEEFVRMMVSK
3D structure
PDB2m5e Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.
ChainA
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E84 L85 E87 A88 V91 M109 E114 E127 M144 E9 L10 E12 A13 V16 M34 E39 E52 M69
BS02 CA A D93 D95 N97 L99 E104 D18 D20 N22 L24 E29
BS03 CA A D129 D131 D133 H135 E140 D54 D56 D58 H60 E65
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2m5e, PDBe:2m5e, PDBj:2m5e
PDBsum2m5e
PubMed28343066
UniProtP07463|CALM_PARTE Calmodulin (Gene Name=CAM)

[Back to BioLiP]