Structure of PDB 2m48 Chain A

Receptor sequence
>2m48A (length=141) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
EEYVLQAGGVLCPQPGCGMGLLVEPDCRKVTCQNGCGYVFCRNCLQGYHI
GECLPEGTGASATNSCEYTVDPNRAAEARWDEASNVTIKVSTKPCPKCRT
PTERDGGCMHMVCTRAGCGFEWCWVCQTEWTRDCMGAHWFG
3D structure
PDB2m48 A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
ChainA
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C353 C358 C373 C12 C17 C32
BS02 ZN A C382 H390 C394 C41 H49 C53
BS03 ZN A C436 C454 C459 C95 C113 C118
BS04 ZN A C464 H479 C123 H138
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2m48, PDBe:2m48, PDBj:2m48
PDBsum2m48
PubMed23770917
UniProtQ7KTX7|PRKN_DROME E3 ubiquitin-protein ligase parkin (Gene Name=park)

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