Structure of PDB 2m0p Chain A

Receptor sequence
>2m0pA (length=46) Species: 9606 (Homo sapiens) [Search protein sequence]
THAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTET
3D structure
PDB2m0p Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A W1126 D1129 D1131 D1133 D1139 E1140 W24 D27 D29 D31 D37 E38
External links
PDB RCSB:2m0p, PDBe:2m0p, PDBj:2m0p
PDBsum2m0p
PubMed23275343
UniProtP98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 (Gene Name=LRP2)

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