Structure of PDB 2lyb Chain A

Receptor sequence
>2lybA (length=131) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence]
GARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLL
ETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEAL
DKIEEEQNKSKKKAQQAAADTGNNSQVSQNY
3D structure
PDB2lyb Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8SP A F44 L64 F43 L63 PDBbind-CN: -logKd/Ki=4.46,Kd=35uM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:2lyb, PDBe:2lyb, PDBj:2lyb
PDBsum2lyb
PubMed23401539
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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