Structure of PDB 2l4k Chain A

Receptor sequence
>2l4kA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
GSPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQR
NPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFH
QLNRGILPCLLRHCCTRVAL
3D structure
PDB2l4k Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A S25 R26 E27 Q30 R46 S48 N51 V56 K66 H67 Y68 L69 I70 S82 M83 S25 R26 E27 Q30 R46 S48 N51 V56 K66 H67 Y68 L69 I70 S82 M83
External links
PDB RCSB:2l4k, PDBe:2l4k, PDBj:2l4k
PDBsum2l4k
PubMed22702899
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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