Structure of PDB 2l1r Chain A

Receptor sequence
>2l1rA (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDS
3D structure
PDB2l1r A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E19 I26 F27 V44 M47 E56 M81 E19 I26 F27 V44 M47 E56 M81
BS02 CA A D65 D67 S69 T71 D73 E76 D65 D67 S69 T71 D73 E76
BS03 SXK A F27 L41 M60 M80 R83 C84 F27 L41 M60 M80 R83 C84 PDBbind-CN: -logKd/Ki=3.57,Kd=270uM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2l1r, PDBe:2l1r, PDBj:2l1r
PDBsum2l1r
PubMed20801130
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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