Structure of PDB 2l1c Chain A

Receptor sequence

>2l1cA (length=191) Species: 9606 (Homo sapiens) [Search protein sequence]

GQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSM
RALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLK
FAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAY
VAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLR

3D structure

PDB

2l1c Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain.

Chain

Resolution

N/A

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	S65 M66 R67 N72 T75 Q76 T78 R79 L84 R98 R99 K100 R104 L106 S107 M147 Q148 I150 S151 F152 A153 S154 G155 T160 K169 R175 F198 F202 L206 R207	S49 M50 R51 N56 T59 Q60 T62 R63 L68 R82 R83 K84 R88 L90 S91 M131 Q132 I134 S135 F136 A137 S138 G139 T144 K153 R159 F182 F186 L190 R191

Gene Ontology

	Biological Process
GO:0035556	intracellular signal transduction

View graph for
Biological Process

External links

PDB	RCSB:2l1c, PDBe:2l1c, PDBj:2l1c
PDBsum	2l1c
PubMed	20739287
UniProt	P29353\|SHC1_HUMAN SHC-transforming protein 1 (Gene Name=SHC1)

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