Structure of PDB 2kxq Chain A

Receptor sequence
>2kxqA (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGGSPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINC
EELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSAN
3D structure
PDB2kxq Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q264 G265 Q266 W279 R306 T308 Y314 V316 H318 R321 T322 T323 F325 Q21 G22 Q23 W36 R63 T65 Y71 V73 H75 R78 T79 T80 F82
External links
PDB RCSB:2kxq, PDBe:2kxq, PDBj:2kxq
PDBsum2kxq
PubMed20937913
UniProtQ9HAU4|SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 (Gene Name=SMURF2)

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