Structure of PDB 2kup Chain A

Receptor sequence
>2kupA (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSGSSGLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLH
RREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNL
LQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSS
3D structure
PDB2kup Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N25 D27 D28 Y59 L60 R64 Y65 G66 Y67 S73 F74 R79 I86 F87 F98 Q102 M105 N25 D27 D28 Y59 L60 R64 Y65 G66 Y67 S73 F74 R79 I86 F87 F98 Q102 M105
External links
PDB RCSB:2kup, PDBe:2kup, PDBj:2kup
PDBsum2kup
PubMed20454865
UniProtO43559|FRS3_HUMAN Fibroblast growth factor receptor substrate 3 (Gene Name=FRS3)

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