Structure of PDB 2kuo Chain A

Receptor sequence
>2kuoA (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
GSKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGV
QIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNV
3D structure
PDB2kuo Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C379 C385 H392 H398 C22 C28 H35 H41
BS02 ZN A C421 C427 H434 H440 C64 C70 H77 H83
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2kuo, PDBe:2kuo, PDBj:2kuo
PDBsum2kuo
PubMed
UniProtQ8IW19|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)

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