Structure of PDB 2kqe Chain A

Receptor sequence
>2kqeA (length=47) Species: 9606 (Homo sapiens) [Search protein sequence]
GGVQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDE
3D structure
PDB2kqe Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
ChainA
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C421 C427 H434 H440 C17 C23 H30 H36
BS02 ADN A Y423 S426 Y428 Y19 S22 Y24
BS03 RIB A Y423 R429 Y19 R25
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2kqe, PDBe:2kqe, PDBj:2kqe
PDBsum2kqe
PubMed20098424
UniProtQ8IW19|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)

[Back to BioLiP]