Structure of PDB 2ko7 Chain A

Receptor sequence
>2ko7A (length=117) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence]
GPGSMTVVTTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQKFDSS
KDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGG
VIPPNATLVFEVELLDV
3D structure
PDB2ko7 The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
ChainA
ResolutionN/A
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y37 F47 D48 I67 Y93 F110
Catalytic site (residue number reindexed from 1) Y37 F47 D48 I67 Y93 F110
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JZF A I67 W70 Y93 I67 W70 Y93 PDBbind-CN: -logKd/Ki=5.19,Ki=6.5uM
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:2ko7, PDBe:2ko7, PDBj:2ko7
PDBsum2ko7
PubMed21574961
UniProtQ63J95

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