Structure of PDB 2ko0 Chain A

Receptor sequence
>2ko0A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKY
SSICSEHFTPDSFKRESNNKLLKENAVPTIFLELVPR
3D structure
PDB2ko0 Structural determinants of specific DNA-recognition by the THAP zinc finger
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A M1 V2 Q3 Y14 F22 H23 K24 T28 K64 R65 L71 M1 V2 Q3 Y14 F22 H23 K24 T28 K64 R65 L71 PDBbind-CN: Kd=480nM
BS02 dna A Q3 K11 F45 K46 P47 T48 Y50 S51 K70 Q3 K11 F45 K46 P47 T48 Y50 S51 K70 PDBbind-CN: Kd=480nM
BS03 ZN A C5 C10 E56 H57 C5 C10 E56 H57
Gene Ontology
Molecular Function
GO:0043565 sequence-specific DNA binding

View graph for
Molecular Function
External links
PDB RCSB:2ko0, PDBe:2ko0, PDBj:2ko0
PDBsum2ko0
PubMed20144952
UniProtQ9NVV9|THAP1_HUMAN THAP domain-containing protein 1 (Gene Name=THAP1)

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