Structure of PDB 2kmx Chain A

Receptor sequence
>2kmxA (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYC
KQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNAS
LVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVIN
NDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
3D structure
PDB2kmx The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 7.2.2.8: P-type Cu(+) transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A E1081 H1086 L1088 I1182 G1183 E35 H40 L42 I136 G137 PDBbind-CN: -logKd/Ki=4.08,Kd=83.3uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:2kmx, PDBe:2kmx, PDBj:2kmx
PDBsum2kmx
PubMed19917612
UniProtQ04656|ATP7A_HUMAN Copper-transporting ATPase 1 (Gene Name=ATP7A)

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