Structure of PDB 2kdh Chain A

Receptor sequence
>2kdhA (length=72) Species: 9606 (Homo sapiens) [Search protein sequence]
MGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKD
GDKNNDGRIDYDEFLEFMKGVE
3D structure
PDB2kdh Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D105 N107 D109 Y111 I112 D113 E116 D16 N18 D20 Y22 I23 D24 E27
BS02 KDH A F104 L121 F156 M157 V160 F15 L32 F67 M68 V71 PDBbind-CN: -logKd/Ki=2.96,Kd=1.1mM
BS03 CA A D141 D145 R147 E152 D52 D56 R58 E63
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2kdh, PDBe:2kdh, PDBj:2kdh
PDBsum2kdh
PubMed19542563
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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