Structure of PDB 2k8r Chain A

Receptor sequence
>2k8rA (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
YKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIK
STETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNW
FVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
3D structure
PDB2k8r Solution structure of human acidic fibroblast growth factor in complex with anti-angiogenic drug inositol hexaphosphate (IP6)
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IHP A K105 K111 R115 Y118 G119 K121 K105 K111 R115 Y118 G119 K121
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:2k8r, PDBe:2k8r, PDBj:2k8r
PDBsum2k8r
PubMed
UniProtP05230|FGF1_HUMAN Fibroblast growth factor 1 (Gene Name=FGF1)

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