Structure of PDB 2k7f Chain A

Receptor sequence
>2k7fA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
KRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERD
EAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDG
LLNLIRNLE
3D structure
PDB2k7f Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y385 R388 K436 T438 R452 S454 G455 Q456 S457 Y11 R14 K62 T64 R78 S80 G81 Q82 S83 PDBbind-CN: Kd=10nM
BS02 dna A K375 Y379 R383 I414 T415 R423 G439 N440 K458 K1 Y5 R9 I40 T41 R49 G65 N66 K84 PDBbind-CN: Kd=10nM
External links
PDB RCSB:2k7f, PDBe:2k7f, PDBj:2k7f
PDBsum2k7f
PubMed20081198
UniProtP35251|RFC1_HUMAN Replication factor C subunit 1 (Gene Name=RFC1)

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