Structure of PDB 2k4i Chain A

Receptor sequence
>2k4iA (length=134) Species: 11720 (Human immunodeficiency virus type 2 (ISOLATE ROD)) [Search protein sequence]
GARNSVLRGKKADELERIRLRPGGKKKYRLKHIVWAANKLDRFGLAESLL
ESKEGCQKILTVLDPMVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAK
QIVRRHLVAETGTAEKMPSTSRPTAPSSEKGGNY
3D structure
PDB2k4i Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.47: HIV-2 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PBU A L21 R22 K27 H33 W36 S77 N80 T81 L20 R21 K26 H32 W35 S76 N79 T80 PDBbind-CN: -logKd/Ki=3.84,Kd=143uM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:2k4i, PDBe:2k4i, PDBj:2k4i
PDBsum2k4i
PubMed18657545
UniProtP04584|POL_HV2RO Gag-Pol polyprotein (Gene Name=gag-pol)

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