Structure of PDB 2jxy Chain A

Receptor sequence
>2jxyA (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
MEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWP
TLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNF
VKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIG
PKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
3D structure
PDB2jxy Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.65: macrophage elastase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D289 A290 E333 D381 A382 D430 D13 A14 E57 D105 A106 D154
External links
PDB RCSB:2jxy, PDBe:2jxy, PDBj:2jxy
PDBsum2jxy
PubMed18465858
UniProtP39900|MMP12_HUMAN Macrophage metalloelastase (Gene Name=MMP12)

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