Structure of PDB 2jvn Chain A

Receptor sequence
>2jvnA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
KLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDR
VADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKE
WVTPKEFREISYLKKLKVKKQDRIFP
3D structure
PDB2jvn Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C295 C298 C311 C321 C63 C66 C79 C89
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2jvn, PDBe:2jvn, PDBj:2jvn
PDBsum2jvn
PubMed18452307
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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