Structure of PDB 2jsc Chain A

Receptor sequence
>2jscA (length=96) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
LARLGRALADPTRCRILVALLDGVCYPGQLAAHLGLTRSNVSNHLSCLRG
CGLVVATYEGRQVRYALADSHLARALGELVQVVLAVDTDQPCVAER
3D structure
PDB2jsc NMR Structural Analysis of Cadmium Sensing by Winged Helix Repressor CmtR.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CD A C57 C61 C47 C51
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0032791 lead ion binding
GO:0046870 cadmium ion binding
GO:0046872 metal ion binding
GO:0097063 cadmium ion sensor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0010288 response to lead ion
GO:0010468 regulation of gene expression
GO:0046686 response to cadmium ion

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2jsc, PDBe:2jsc, PDBj:2jsc
PDBsum2jsc
PubMed17599915
UniProtP9WMI9|CMTR_MYCTU HTH-type transcriptional regulator CmtR (Gene Name=cmtR)

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