Structure of PDB 2jr7 Chain A

Receptor sequence
>2jr7A (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPS
CSLIIKVIYDKDQFVSGETVPAPSANKELVKLEH
3D structure
PDB2jr7 Solution structure of human DESR1, a CSL zinc-binding protein
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C26 C48 C51 C26 C48 C51
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008198 ferrous iron binding
GO:0034986 iron chaperone activity
GO:0046872 metal ion binding
Biological Process
GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0017183 protein histidyl modification to diphthamide
GO:0050709 negative regulation of protein secretion
GO:0051099 positive regulation of binding
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol

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External links
PDB RCSB:2jr7, PDBe:2jr7, PDBj:2jr7
PDBsum2jr7
PubMed18214955
UniProtQ96FX2|DPH3_HUMAN Diphthamide biosynthesis protein 3 (Gene Name=DPH3)

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