Structure of PDB 2jky Chain A

Receptor sequence
>2jkyA (length=207) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPARILRTFLKEP
GVPTIRIFAIILSLYEDLNSVGSEVGVKVSRTQWIDYEQCKLDLVGKNVL
IVDEVDDTRTTLHYALSELEKDAAEQAKAKGIDTEKSPEMKTNFGIFVLH
DKQKPKKADLPAEMLNDKNRYFAAKTVPDKWYAYPWESTDIVFHTRMAIE
QGNDIFI
3D structure
PDB2jky Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.8: hypoxanthine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP A Y69 K85 E111 V112 D114 T115 R116 T117 T118 K159 W188 Y189 Y191 E194 Y65 K78 E104 V105 D107 T108 R109 T110 T111 K152 W181 Y182 Y184 E187
BS02 SO4 A G38 E70 G34 E66
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004422 hypoxanthine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
GO:0052657 guanine phosphoribosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0009058 biosynthetic process
GO:0032263 GMP salvage
GO:0032264 IMP salvage
GO:0032265 XMP salvage
GO:0046100 hypoxanthine metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2jky, PDBe:2jky, PDBj:2jky
PDBsum2jky
PubMed22610485
UniProtQ04178|HPRT_YEAST Hypoxanthine-guanine phosphoribosyltransferase (Gene Name=HPT1)

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