Structure of PDB 2jgb Chain A

Receptor sequence
>2jgbA (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
KAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQF
WRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLA
SRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTA
RIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGPQRLLF
3D structure
PDB2jgb Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H54 P55 Q57 Y58 V91 E92 W95 N150 L153 G157 E158 Q159 M161 G163 H10 P11 Q13 Y14 V47 E48 W51 N106 L109 G113 E114 Q115 M117 G119
BS02 MGT A T73 Y78 H110 M123 W124 E125 R174 F234 T29 Y34 H66 M79 W80 E81 R130 F187
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2jgb, PDBe:2jgb, PDBj:2jgb
PDBsum2jgb
PubMed17368478
UniProtO60573|IF4E2_HUMAN Eukaryotic translation initiation factor 4E type 2 (Gene Name=EIF4E2)

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