Structure of PDB 2jg1 Chain A

Receptor sequence
>2jg1A (length=318) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence]
GLVPRGSHMILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNV
TRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAFYNIKGETRNCIA
ILHEGQQTEILEQGPEIDNQEAAGFIKHFEQMMEKVEAVAISGSLPKGLN
QDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQL
LNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVNIP
TISVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGY
VNLNNYDDLFNQIEVLEV
3D structure
PDB2jg1 Structures of Staphylococcus Aureus D-Tagatose-6-Phosphate Kinase Implicate Domain Motions in Specificity and Mechanism.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G251 S252 G253 D254
Catalytic site (residue number reindexed from 1) G259 S260 G261 D262
Enzyme Commision number 2.7.1.144: tagatose-6-phosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A K38 N185 S222 G224 G227 I244 V246 G251 S252 G253 D254 T256 N278 G281 M282 K46 N193 S230 G232 G235 I252 V254 G259 S260 G261 D262 T264 N286 G289 M290
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008443 phosphofructokinase activity
GO:0009024 tagatose-6-phosphate kinase activity
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005988 lactose metabolic process
GO:0016310 phosphorylation
GO:0019512 lactose catabolic process via tagatose-6-phosphate
GO:0046835 carbohydrate phosphorylation
GO:2001059 D-tagatose 6-phosphate catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2jg1, PDBe:2jg1, PDBj:2jg1
PDBsum2jg1
PubMed17459874
UniProtP0A0B9|LACC_STAA8 Tagatose-6-phosphate kinase (Gene Name=lacC)

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