Structure of PDB 2jch Chain A

Receptor sequence
>2jchA (length=461) Species: 171101 (Streptococcus pneumoniae R6) [Search protein sequence]
SEITYSDGTVIASIDYLYFTTLAEAQERMYDYLAQRDNVSAATQKFYRDL
AAKEIENGGYKITTTIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMD
NQTGAILGFVGGRNYQENQNNHAFDTKRSPASTTKPLLAYGIAIDQGLMG
SETILSNYPTNFANGNPIMYANSKGTGMMTLGEALNYSWNIPAYWTYRML
RENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQHTNGYQTLANNG
VYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVLSSRV
TTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGH
DDNHSLSQQAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEV
LKSTGQKPGKVSVEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDAD
YQNAWSSIVGS
3D structure
PDB2jch Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.129: Transferred entry: 2.4.99.28.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PL7 A S460 Y498 S516 N518 T652 G653 T654 N656 S132 Y170 S188 N190 T324 G325 T326 N328
Gene Ontology
Molecular Function
GO:0008658 penicillin binding

View graph for
Molecular Function
External links
PDB RCSB:2jch, PDBe:2jch, PDBj:2jch
PDBsum2jch
PubMed17676039
UniProtO70038

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