Structure of PDB 2jc4 Chain A

Receptor sequence
>2jc4A (length=256) Species: 487 (Neisseria meningitidis) [Search protein sequence]
MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPAAALQMM
GWHCVWSGQKTYNGVAIVSRSVPQDVHFGLPALPDDPQRRVIAATVSGVR
VINVYCVNGEALDSPKFKYKEQWFAALTEFVRDEMTRHGKLVLLGDFNIA
PADADCYDPEKWHEKIHCSSVERQWFQNLLDLGLTDSLRQVHPEGAFYTW
FDYRGAMFQRKLGLRIDHILVSPAMAAALKDVRVDLETRALERPSDHAPV
TAEFDW
3D structure
PDB2jc4 Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N7 N9 E34 Y105 D146 N148 D217 D246 H247
Catalytic site (residue number reindexed from 1) N7 N9 E34 Y105 D146 N148 D217 D246 H247
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N9 E34 N9 E34
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2jc4, PDBe:2jc4, PDBj:2jc4
PDBsum2jc4
PubMed17318183
UniProtQ9K100

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