Structure of PDB 2jax Chain A

Receptor sequence

>2jaxA (length=261) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]

LGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSRWQQDHGRHLID
DALKVVEQASLRAGPPTVHSEIVPAAAVPTLVDMSKDAVLMVVGCLGSGR
WPGRLLGSVSSGLLRHAHCPVVIIHDAPVLVGVDGSSASELATAIAFDEA
SRRNVDLVALHAWSDVDVSEWPGIDWPATQSMAEQVLAERLAGWQERYPN
VAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQ
LARTPVIVARE

3D structure

PDB

2jax Crystal Structure of Universal Stress Protein Rv2623 from Mycobacterium Tuberculosis

Chain

Resolution

3.22 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	G165 V166 D167 A195 P245 V261 G262 R264 G265 G267 G268 M272 G275 S276 V277	G132 V133 D134 A162 P212 V228 G229 R231 G232 G234 G235 M239 G242 S243 V244
BS02	ATP	A	G13 I14 D15 A20 H42 A43 A100 V116 G117 G120 S121 R123 R127 G130 S131 V132	G6 I7 D8 A13 H35 A36 A77 V93 G94 G97 S98 R100 R104 G107 S108 V109

Gene Ontology

	Molecular Function
GO:0005524	ATP binding

	Biological Process
GO:0001666	response to hypoxia
GO:0040008	regulation of growth
GO:0085014	dormancy entry of symbiont in host

	Cellular Component
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0009274	peptidoglycan-based cell wall

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:2jax, PDBe:2jax, PDBj:2jax
PDBsum	2jax
PubMed
UniProt	P9WFD7\|Y2623_MYCTU Universal stress protein Rv2623 (Gene Name=Rv2623)

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