Structure of PDB 2jam Chain A

Receptor sequence
>2jamA (length=279) Species: 9606 (Homo sapiens) [Search protein sequence]
NIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSSLENEIAVLK
KIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLV
IQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQN
GIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEET
ESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALS
HPWIDGNTALHRDIYPSVSLQIQKNFAKS
3D structure
PDB2jam Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D144 K146 N149 D165 T183
Catalytic site (residue number reindexed from 1) D120 K122 N125 D141 T159
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N18 K74 D86 I87 Y88 E89 S90 N1 K50 D62 I63 Y64 E65 S66
BS02 J60 A V37 A50 K52 M98 L100 V101 T164 D165 V20 A33 K35 M74 L76 V77 T140 D141
BS03 CA A L284 H285 L260 H261
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2jam, PDBe:2jam, PDBj:2jam
PDBsum2jam
PubMed
UniProtQ96NX5|KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G (Gene Name=CAMK1G)

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