Structure of PDB 2jac Chain A

Receptor sequence
>2jacA (length=108) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MVSQETIKHVKDLIAENEIFVASKTYCPYSHAALNTLFEKLKVPRSKVLV
LQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGEL
EELLEPIL
3D structure
PDB2jac Structure of Glutaredoxin Grx1P C30S Mutant from Yeast.
ChainA
Resolution2.02 Å
3D
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Enzymatic activity
Enzyme Commision number 1.11.1.9: glutathione peroxidase.
2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A K24 C27 Y29 Q63 T74 V75 N88 D89 K24 C27 Y29 Q63 T74 V75 N88 D89
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0005515 protein binding
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
GO:0016740 transferase activity
Biological Process
GO:0034599 cellular response to oxidative stress
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2jac, PDBe:2jac, PDBj:2jac
PDBsum2jac
PubMed17327665
UniProtP25373|GLRX1_YEAST Glutaredoxin-1 (Gene Name=GRX1)

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