Structure of PDB 2ja3 Chain A

Receptor sequence
>2ja3A (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
HKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRE
SQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTL
KLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKD
VLKHIAQMANFNEFLEV
3D structure
PDB2ja3 Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
ChainA
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A K587 L595 T596 Y617 D727 K10 L18 T19 Y40 D150 PDBbind-CN: -logKd/Ki=4.00,Kd=100uM
External links
PDB RCSB:2ja3, PDBe:2ja3, PDBj:2ja3
PDBsum2ja3
PubMed17195847
UniProtP51795|CLCN5_HUMAN H(+)/Cl(-) exchange transporter 5 (Gene Name=CLCN5)

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