Structure of PDB 2j9r Chain A

Receptor sequence
>2j9rA (length=178) Species: 260799 (Bacillus anthracis str. Sterne) [Search protein sequence]
SHMYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCVKA
VPVSASKDIFKHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAG
LDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAA
FDDPIILVGASESYEPRCRHCHAVPTKQ
3D structure
PDB2j9r Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.21: thymidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C145 C148 C183 C186 C130 C133 C168 C171
BS02 THM A E89 F92 L116 D119 F120 F125 T155 I170 I171 L172 G174 Y179 E74 F77 L101 D104 F105 F110 T140 I155 I156 L157 G159 Y164
Gene Ontology
Molecular Function
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0016310 phosphorylation
GO:0046104 thymidine metabolic process
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:2j9r, PDBe:2j9r, PDBj:2j9r
PDBsum2j9r
PubMed17288553
UniProtQ81JX0|KITH_BACAN Thymidine kinase (Gene Name=tdk)

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