Structure of PDB 2j8z Chain A

Receptor sequence
>2j8zA (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
QSMLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ
GQYDPPPGASNILGLEASGHVAELGPGCQHWKIGDTAMALLPGGGQAQYV
TVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAG
LSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE
ATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP
LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTQRLLPVLD
RIYPVTEIQEAHKYMEANKNIGKIVLELPQ
3D structure
PDB2j8z Three-Dimensional Structure and Enzymatic Function of Proapoptotic Human P53-Inducible Quinone Oxidoreductase Pig3.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.5.5: NADPH:quinone reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A N41 R42 E124 T128 A149 S152 G153 V154 A173 G174 K178 Y193 C217 I218 Y239 M242 L266 L267 M318 N321 N42 R43 E124 T128 A149 S152 G153 V154 A173 G174 K178 Y193 C217 I218 Y239 M242 L266 L267 M315 N318
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003960 NADPH:quinone reductase activity
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
GO:0048038 quinone binding
GO:0070402 NADPH binding
Biological Process
GO:0006739 NADP metabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:2j8z, PDBe:2j8z, PDBj:2j8z
PDBsum2j8z
PubMed19349281
UniProtQ53FA7|QORX_HUMAN Quinone oxidoreductase PIG3 (Gene Name=TP53I3)

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