Structure of PDB 2ixv Chain A

Receptor sequence
>2ixvA (length=338) Species: 10747 (Streptococcus phage Cp1) [Search protein sequence]
VKKNDLFVDVSSHNGYDITGILEQMGTTNTIIKISESTTYLNPCLSAQVE
QSNPIGFYHFARFGGDVAEAEREAQFFLDNVPMQVKYLVLDYQDDPSGDA
QANTNACLRFMQMIADAGYKPIYYSYKPFTHDNVDYQQILAQFPNSLWIA
GYGLNDGTANFEYFPSMDGIRWWQYSSNPFDKNIVLLDDEEDDKPKTAGT
WKQDSKGWWFRRNNGSFPYNKWEKIGGVWYYFDSKGYCLTSEWLKDNEKW
YYLKDNGAMATGWVLVGSEWYYMDDSGAMVTGWVKYKNNWYYMTNERGNM
VSNEFIKSGKGWYFMNTNGELADNPSFTKEPDGLITVA
3D structure
PDB2ixv Elucidation of the Molecular Recognition of Bacterial Cell Wall by Modular Pneumococcal Phage Endolysin Cpl-1.
ChainA
Resolution1.96 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D10 D92 Q94 D182
Catalytic site (residue number reindexed from 1) D9 D91 Q93 D181
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MUB A Y127 P129 A151 G152 Y153 Y126 P128 A150 G151 Y152
BS02 ALA A Y153 G154 Y152 G153
BS03 DGN A G154 Y164 G153 Y163
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2ixv, PDBe:2ixv, PDBj:2ixv
PDBsum2ixv
PubMed17581815
UniProtP15057|LYS_BPCP1 Lysozyme (Gene Name=CPL1)

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