Structure of PDB 2ix6 Chain A

Receptor sequence
>2ix6A (length=416) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
KSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKV
RECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSIT
ANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQL
NTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLI
IFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVP
DEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQF
GAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKA
WISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTL
VTGREVTGIASFKPAT
3D structure
PDB2ix6 Controlling Electron Transfer in Acyl-Coa Oxidases and Dehydrogenases: A Structural View.
ChainA
Resolution3.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) L174 T175 S287 E408 R420
Catalytic site (residue number reindexed from 1) L158 T159 S271 E392 R404
Enzyme Commision number 1.3.3.6: acyl-CoA oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A T175 G180 S181 W205 N255 Y407 T410 D412 T159 G164 S165 W189 N239 Y391 T394 D396
BS02 FAD A R313 F316 L320 F323 N326 E381 L382 G385 I388 R297 F300 L304 F307 N310 E365 L366 G369 I372
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0003997 acyl-CoA oxidase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:1901149 salicylic acid binding
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0009793 embryo development ending in seed dormancy
GO:0046459 short-chain fatty acid metabolic process
Cellular Component
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0009514 glyoxysome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2ix6, PDBe:2ix6, PDBj:2ix6
PDBsum2ix6
PubMed16887802
UniProtQ96329|ACOX4_ARATH Acyl-coenzyme A oxidase 4, peroxisomal (Gene Name=ACX4)

[Back to BioLiP]