Structure of PDB 2iwa Chain A

Receptor sequence
>2iwaA (length=254) Species: 3649 (Carica papaya) [Search protein sequence]
RPSSRVYIVEVLNEFPHDPYAFTQGLVYAENDTLFESTGLYGRSSVRQVA
LQTGKVENIHKMDDSYFGEGLTLLNEKLYQVVWLKNIGFIYDRRTLSNIK
NFTHQMKDGWGLATDGKILYGSDGTSILYEIDPHTFKLIKKHNVKYNGHR
VIRLNELEYINGEVWANIWQTDCIARISAKDGTLLGWILLPNLRKKLIDE
GFRDIDVLNGIAWDQENKRIFVTGKLWPKLFEIKLHLVRHRIPDGYIERH
CLNL
3D structure
PDB2iwa Papaya Glutamine Cyclotransferase Shows a Singular Five-Fold Beta-Propeller Architecture that Suggests a Novel Reaction Mechanism.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.5: glutaminyl-peptide cyclotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A L48 E178 L179 E180 I233 L26 E156 L157 E158 I211
Gene Ontology
Molecular Function
GO:0016603 glutaminyl-peptide cyclotransferase activity
GO:0016746 acyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase

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Molecular Function
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Biological Process
External links
PDB RCSB:2iwa, PDBe:2iwa, PDBj:2iwa
PDBsum2iwa
PubMed17081122
UniProtO81226

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